Primary study · included by 1 review

Three-year clinical performance of direct restorations using low-shrinkage Giomer vs. nano-hybrid resin composite.

Toz-Akalin et al. [24] · Toz-Akalin Tugba, Öztürk-Bozkurt Funda, Kusdemir Mahmut, et al. · Frontiers in dental medicine · 2024

Included by

Clinical Efficacy of Bioactive and Smart Restorative Materials in Preventing Secondary Caries: A Systematic Review and Meta-Analysis.
Non-Cochrane · intervention · 2026 · cited as Toz-Akalin et al. [24] · Table 1; Figure 4; reference 24
Outcome this study informsPooled effectEvidenceCertainty
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.54 [0.45, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.59 [0.51, 0.68]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.44, 0.69]40 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.54 [0.46, 0.63]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.57 [0.45, 0.72]33 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.66]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam) · Follow-up 9 months to 10 years
RR 0.55 [0.46, 0.65]40 studies · 5506 participantsModerate
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam) · Long-term follow-up (>2 years)
RR 0.5 [0.39, 0.65]22 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.56 [0.47, 0.66]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.44, 0.69]23 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.53 [0.45, 0.63]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.47, 0.66]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.54 [0.46, 0.64]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.53 [0.41, 0.68]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.54 [0.46, 0.64]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.57 [0.49, 0.67]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.56 [0.47, 0.66]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.51 [0.33, 0.78]17 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.52 [0.37, 0.82]40 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam)
RR 0.55 [0.46, 0.65]39 studiesGRADE not reported
Incidence of secondary caries
Bioactive/smart restorative materials (GIC, RMGIC, giomer, bioactive resin, alkasite, other) vs Conventional restorative materials (resin composite, amalgam) · Short-term follow-up (<=2 years)
RR 0.67 [0.48, 0.94]18 studiesGRADE not reported

1 including review in total.