Primary study · included by 1 review

Does Varying Platelet-Rich Fibrin Centri̇fugati̇on Protocols Enhance New Bone Formati̇on in Extracti̇on Site?

Aliyev 2025 · Aliyev Toghrul, Ulu Murat, Rizaj Xhini, et al. · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · 2025

Included by

The efficacy of platelet-rich fibrin in alveolar ridge preservation: a systematic review and meta-analysis of randomized controlled trials.

Non-Cochrane · intervention · 2026 · cited as Aliyev 2025 · Figures 3, 5, 7; reference 25

Outcome this study informs	Pooled effect	Evidence	Certainty
Percentage of new bone formation (BV/TV, histomorphometry) PRF alone placed in the extraction socket (any preparation protocol) vs Spontaneous healing (blood clot) · 2 months	MD 22.11 [-10.27, 54.49]	2 studies · 74 participants	GRADE not reported
Percentage of new bone formation (BV/TV, histomorphometry) PRF alone placed in the extraction socket (any preparation protocol) vs Spontaneous healing (blood clot) · 2 to 4 months (pooled over time points)	MD 15.92 [1.87, 29.97]	7 studies · 237 participants	Low
Percentage of new bone formation (BV/TV, histomorphometry) PRF alone placed in the extraction socket (any preparation protocol) vs Spontaneous healing (blood clot) · 3 months	MD 11.36 [4.70, 18.02]	3 studies · 83 participants	GRADE not reported
Percentage of new bone formation (BV/TV, histomorphometry) PRF alone placed in the extraction socket (any preparation protocol) vs Spontaneous healing (blood clot) · 4 months	MD 16.97 [4.14, 29.81]	2 studies · 80 participants	GRADE not reported
Percentage of new bone formation (BV/TV, histomorphometry) PRF alone placed in the extraction socket (any preparation protocol) vs Spontaneous healing (blood clot)	MD 17.07 [1.96, 32.19]	6 studies · 217 participants	GRADE not reported

1 including review in total.