Primary study · included by 1 review

Comparison of the Efficacy Between Articaine and Lignocaine in Simultaneous Bilateral Orthodontic Maxillary Premolar Extractions: A Split-Mouth Comparative Study.

Krishna 2023 · Krishna Sai, Bhaskaran Rajprakash, Kumar Santhosh P, et al. · Cureus · 2023

Included by

Non-Cochrane · intervention · 2026 · cited as Krishna 2023 · Reference 20; Results (studies cited per outcome); Table 1

Outcome this study informs	Pooled effect	Evidence	Certainty
Anesthetic duration (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD 8.2 [-4.76, 21.16]	3 studies	GRADE not reported
Anesthetic duration (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD 27.34 [9.52, 45.16]	4 studies	GRADE not reported
Anesthetic duration (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD 27.34 [9.52, 45.16]	4 studies	GRADE not reported
Anesthetic duration 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD 18.68 [3.05, 34.30]	7 studies · 476 participants	Moderate
Anesthetic duration (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD 10.02 [-3.71, 23.74]	2 studies	GRADE not reported

1 including review in total.