Primary study · included by 1 review

Articaine versus Lidocaine in only buccal infiltration anesthesia for the extraction of mandibular anterior teeth. A prospective split-mouth randomized-controlled clinical study.

Al-Mahalawy 2023 · Al-Mahalawy Haytham, El-Mahallawy Yehia, Abdelrahman Hams H, et al. · BMC oral health · 2023

Included by

Efficacy comparison of articaine versus lidocaine in dental anesthesia: a meta-analysis of randomized controlled trials.
Non-Cochrane · intervention · 2026 · cited as Al-Mahalawy 2023 · Reference 12; Results (studies cited per outcome); Table 1
Outcome this study informsPooled effectEvidenceCertainty
Pain intensity (VAS)
4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia
MD -2.6 [-5.07, -0.12]4 studiesGRADE not reported
Pain intensity (VAS)
4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia
MD -3.16 [-6.09, -0.23]7 studiesGRADE not reported
Pain intensity (VAS)
4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia
MD -2.38 [-3.43, -1.33]3 studiesGRADE not reported
Pain intensity (VAS)
4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia
MD -0.95 [-7.73, 5.84]3 studiesGRADE not reported
Pain intensity (VAS)
4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia
MD -4.41 [-7.62, -1.21]7 studies · 418 participantsModerate
Pain intensity (VAS)
4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia
MD -5.2 [-8.01, -2.38]3 studiesGRADE not reported
Pain intensity (VAS)
4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia
MD -8.72 [-16.04, -1.4]3 studiesGRADE not reported

1 including review in total.