Primary study · included by 2 reviews

Treatment effects after maxillary expansion using invisalign first system vs. acrylic splint expander in mixed dentition: a prospective cohort study.

Lu et al. 2023 · Lu Lanxin, Zhang Lingling, Li Chengri, et al. · BMC oral health · 2023

Included by

Non-Cochrane · intervention · 2026 · cited as Lu 2023 · Table 1; Results forest plots Figs. 4-9

Outcome this study informs	Pooled effect	Evidence	Certainty
Quantity of expansion: intermolar distance (6-6) Clear aligners (Invisalign First) vs Conventional maxillary expanders (RME/Hyrax, leaf, removable acrylic, slow expansion) · Change from baseline to end of treatment	MD -1.77 [-2.57, -0.97]	7 studies · 333 participants	Moderate
Arch depth Clear aligners (Invisalign First) vs Conventional maxillary expanders (RME/Hyrax, leaf, removable acrylic, slow expansion) · Change from baseline to end of treatment	MD -0.14 [-0.66, 0.38]	2 studies · 68 participants	Low
Arch perimeter Clear aligners (Invisalign First) vs Conventional maxillary expanders (RME/Hyrax, leaf, removable acrylic, slow expansion) · Change from baseline to end of treatment	MD -1.75 [-2.71, -0.80]	2 studies · 102 participants	Low
Intercanine distance (C-C) Clear aligners (Invisalign First) vs Conventional maxillary expanders (RME/Hyrax, leaf, removable acrylic, slow expansion) · Change from baseline to end of treatment	MD -0.74 [-1.68, 0.20]	7 studies · 333 participants	GRADE not reported
Intercanine distance (C-C) Clear aligners (Invisalign First) vs Conventional maxillary expanders (RME/Hyrax, leaf, removable acrylic, slow expansion) · Change from baseline to end of treatment	MD -0.507 [-1.44, 0.426]	7 studies · 333 participants	GRADE not reported

Non-Cochrane · intervention · 2026 · cited as Lu 2023 · Table 2; References (ref 25)

The review does not say which of its outcomes this study informs.

2 including reviews in total.