Primary study · included by 1 review

A Split-Mouth Clinical Comparative Evaluation of the Anesthetic Efficacy of Articaine and Lignocaine for Maxillary Bicuspids Extraction.

Jaiswal 2023 · Jaiswal Pooja, Goyal Rohit, Dubey Chanda, et al. · Cureus · 2023

Included by

Efficacy comparison of articaine versus lidocaine in dental anesthesia: a meta-analysis of randomized controlled trials.

Non-Cochrane · intervention · 2026 · cited as Jaiswal 2023 · Reference 17; Results (studies cited per outcome); Table 1

Outcome this study informs	Pooled effect	Evidence	Certainty
Anesthetic duration (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD 8.2 [-4.76, 21.16]	3 studies	GRADE not reported
Anesthetic onset time (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD -1.81 [-2.85, -0.78]	5 studies	GRADE not reported
Anesthetic duration (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD 27.34 [9.52, 45.16]	4 studies	GRADE not reported
Anesthetic duration (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD 27.34 [9.52, 45.16]	4 studies	GRADE not reported
Anesthetic duration 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD 18.68 [3.05, 34.30]	7 studies · 476 participants	Moderate
Anesthetic onset time (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD -0.57 [-0.99, -0.16]	2 studies	GRADE not reported
Anesthetic onset time 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD -1.34 [-2.21, -0.47]	7 studies · 705 participants	Low
Anesthetic duration (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD 10.02 [-3.71, 23.74]	2 studies	GRADE not reported
Anesthetic onset time (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD -2.2 [-3.36, -1.03]	3 studies	GRADE not reported
Anesthetic onset time (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD -0.59 [-2.12, 0.95]	4 studies	GRADE not reported

1 including review in total.