Primary study · included by 1 review

Outcomes of periodontal therapy in rheumatoid arthritis: The OPERA feasibility randomized trial.

de Pablo 2023 · de Pablo Paola, Serban Stefan, Lopez-Oliva Isabel, et al. · Journal of clinical periodontology · 2023

Included by

The Impact of Periodontal Therapy on Disease Activity in Patients with Rheumatoid Arthritis and Concomitant Periodontitis: A Systematic Review and Meta-Analysis.

Non-Cochrane · intervention · 2026 · cited as de Pablo 2023 (OPERA) · Table 1; ref 15; Figures 3-4

Outcome this study informs	Pooled effect	Evidence	Certainty
DAS28-ESR (change or follow-up not specified) Periodontal therapy steps 1-2 (supragingival PMPR and subgingival instrumentation) vs No periodontal treatment, delayed treatment, or oral hygiene instructions alone · 3 months	MD -1.14 [-1.51, -0.78]	3 studies	GRADE not reported
DAS28-CRP, change from baseline Periodontal therapy steps 1-2 (supragingival PMPR and subgingival instrumentation) vs No periodontal treatment, delayed treatment, or oral hygiene instructions alone · 3 months	MD -0.48 [-0.88, -0.07]	2 studies	GRADE not reported
DAS28-CRP, change from baseline Periodontal therapy steps 1-2 (supragingival PMPR and subgingival instrumentation) vs No periodontal treatment, delayed treatment, or oral hygiene instructions alone · 3 months	MD -0.51 [-0.90, -0.13]	3 studies	GRADE not reported
DAS28-CRP, change from baseline Periodontal therapy steps 1-2 (supragingival PMPR and subgingival instrumentation) vs No periodontal treatment, delayed treatment, or oral hygiene instructions alone · 3 months	MD -0.55 [-0.90, -0.21]	4 studies	GRADE not reported
DAS28-CRP, change from baseline Periodontal therapy steps 1-2 (supragingival PMPR and subgingival instrumentation) vs No periodontal treatment, delayed treatment, or oral hygiene instructions alone · 6 months	MD -0.57 [-0.91, -0.23]	2 studies	GRADE not reported
DAS28-CRP, change from baseline Periodontal therapy steps 1-2 (supragingival PMPR and subgingival instrumentation) vs No periodontal treatment, delayed treatment, or oral hygiene instructions alone · 6 months	MD -0.58 [-1.18, 0.03]	2 studies	GRADE not reported
DAS28-CRP, change from baseline Periodontal therapy steps 1-2 (supragingival PMPR and subgingival instrumentation) vs No periodontal treatment, delayed treatment, or oral hygiene instructions alone · 3 months	MD -0.55 [-0.92, -0.19]	4 studies · 189 participants	Low
DAS28-CRP, change from baseline Periodontal therapy steps 1-2 (supragingival PMPR and subgingival instrumentation) vs No periodontal treatment, delayed treatment, or oral hygiene instructions alone · 6 months	MD -0.57 [-1.01, -0.14]	2 studies	GRADE not reported
DAS28-ESR, follow-up value Periodontal therapy steps 1-2 (supragingival PMPR and subgingival instrumentation) vs No periodontal treatment, delayed treatment, or oral hygiene instructions alone · 3 months	MD -0.89 [-2.23, 0.45]	5 studies	GRADE not reported
DAS28-ESR, change from baseline Periodontal therapy steps 1-2 (supragingival PMPR and subgingival instrumentation) vs No periodontal treatment, delayed treatment, or oral hygiene instructions alone · 3 months	MD -1.27 [-2.22, -0.31]	5 studies · 211 participants	Very low
DAS28-ESR, change from baseline Periodontal therapy steps 1-2 (supragingival PMPR and subgingival instrumentation) vs No periodontal treatment, delayed treatment, or oral hygiene instructions alone · 3 months	MD -1.27 [-2.54, 0.01]	5 studies	GRADE not reported
DAS28-ESR, follow-up value Periodontal therapy steps 1-2 (supragingival PMPR and subgingival instrumentation) vs No periodontal treatment, delayed treatment, or oral hygiene instructions alone · 3 months	MD -0.89 [-1.85, 0.07]	5 studies · 211 participants	Very low

1 including review in total.