Primary study · included by 1 review

Non-surgical mechanical therapy of peri-implantitis with or without repeated adjunctive diode laser application. A 6-month double-blinded randomized clinical trial.

Roccuzzo 2022 · Roccuzzo Andrea, Klossner Sabrina, Stähli Alexandra, et al. · Clinical oral implants research · 2022

Included by

Outcome this study informsPooled effectEvidenceCertainty
Fusobacterium nucleatum counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · Baseline
SMD 0.11 [-0.372, 0.592]2 studies · 125 participantsGRADE not reported
Fusobacterium nucleatum counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · 3 months
SMD -0.044 [-0.525, 0.436]2 studies · 125 participantsGRADE not reported
Fusobacterium nucleatum counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · All timepoints combined (baseline, 3 and 6 months)
SMD 0.066 [-0.212, 0.343]2 studies · 125 participantsGRADE not reported
Fusobacterium nucleatum counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · 6 months
SMD 0.132 [-0.348, 0.613]2 studies · 125 participantsGRADE not reported
Fusobacterium nucleatum counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · 6 months
SMD 0.132 [-0.348, 0.613]2 studies · 125 participantsVery low
Porphyromonas gingivalis counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · All timepoints combined (baseline, 3 and 6 months)
SMD -0.152 [-0.636, 0.332]3 studies · 189 participantsGRADE not reported
Fusobacterium nucleatum counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · Baseline
SMD 0.127 [-0.427, 0.681]2 studies · 125 participantsGRADE not reported
Treponema denticola counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · 6 months
SMD -1.384 [-1.968, -0.8]2 studies · 89 participantsGRADE not reported
Treponema denticola counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · 6 months
SMD -1.559 [-4.994, 1.876]2 studies · 89 participantsVery low
Treponema denticola counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · 3 months
SMD -3.196 [-9.237, 2.846]2 studies · 89 participantsGRADE not reported
Treponema denticola counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · Baseline
SMD 0.103 [-0.358, 0.564]2 studies · 89 participantsGRADE not reported
Porphyromonas gingivalis counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · 3 months
SMD -1.034 [-2.863, 0.796]3 studies · 189 participantsGRADE not reported
Porphyromonas gingivalis counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · Baseline
SMD 0.005 [-0.364, 0.375]3 studies · 189 participantsGRADE not reported
Porphyromonas gingivalis counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · All timepoints combined (baseline, 3 and 6 months)
SMD -0.416 [-0.64, -0.192]3 studies · 189 participantsGRADE not reported
Treponema denticola counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · 3 months
SMD -1.645 [-2.328, -0.962]2 studies · 89 participantsGRADE not reported
Fusobacterium nucleatum counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · All timepoints combined (baseline, 3 and 6 months)
SMD 0.067 [-0.223, 0.356]2 studies · 125 participantsGRADE not reported
Porphyromonas gingivalis counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · 6 months
SMD -0.476 [-1.444, 0.492]3 studies · 189 participantsVery low
Porphyromonas gingivalis counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · Baseline
SMD 0.058 [-0.529, 0.646]3 studies · 189 participantsGRADE not reported
Porphyromonas gingivalis counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · 3 months
SMD -0.837 [-1.253, -0.421]3 studies · 189 participantsGRADE not reported
Porphyromonas gingivalis counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · 6 months
SMD -0.512 [-0.894, -0.13]3 studies · 189 participantsGRADE not reported
Fusobacterium nucleatum counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · 3 months
SMD -0.044 [-0.525, 0.436]2 studies · 125 participantsGRADE not reported
Treponema denticola counts
Laser-assisted non-surgical treatment (Er:YAG, diode, photodynamic therapy), alone or adjunctive to mechanical debridement vs Conventional non-surgical mechanical debridement without laser · Baseline
SMD 0.085 [-0.445, 0.614]2 studies · 89 participantsGRADE not reported

1 including review in total.