Primary study · included by 1 review

Prophylactic strategies for hand-foot syndrome/skin reaction associated with systemic cancer treatment: a meta-analysis of randomized controlled trials.

Pandy 2022 · Pandy Jessa Gilda P, Franco Paula Isabel G, Li Rubi K · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022

Included by

The Efficacy and Safety of Nutritional Supplements for Cancer Supportive Care: An Umbrella Review and Hierarchical Evidence Synthesis.

Non-Cochrane · umbrella · 2026 · cited as Pandy 2022 · Reference 77; Tables 2-8

Outcome this study informs	Pooled effect	Evidence	Certainty
Hand-foot syndrome incidence Vitamin B6 (pyridoxine 60 to 200 mg/d) vs Placebo, no treatment or Eppikajutsuto (Kampo medicine)	Incidence of HFS: OR NS (8 RCTs, n = 661)	8 studies · 661 participants	Very low

1 including review in total.