evidencegaps
Primary study · included by 1 review

Oral Administration of Probiotics Reduces Chemotherapy-Induced Diarrhea and Oral Mucositis: A Systematic Review and Meta-Analysis.

Feng 2022 · Feng Jing, Gao Min, Zhao Chengcheng, et al. · Frontiers in nutrition · 2022

Included by

The Efficacy and Safety of Nutritional Supplements for Cancer Supportive Care: An Umbrella Review and Hierarchical Evidence Synthesis.
Non-Cochrane · umbrella · 2026 · cited as Feng 2022 · Reference 59; Tables 2-8
Outcome this study informsPooled effectEvidenceCertainty
Oral mucositis incidence (CTCAE/RTOG)
Probiotics (various strains and formulations) vs Placebo or usual care
RR 0.84 [0.78, 0.91]4 studies · 412 participantsGRADE not reported
Severe oral mucositis (grades 3 and 4)
Probiotics (various strains and formulations) vs Placebo or usual care
Severe OM (Grades 3 & 4): RR NS (7 RCTs, n = 647)7 studies · 647 participantsGRADE not reported

1 including review in total.