evidencegaps
Primary study · included by 1 review

Home Oral Care of Periodontal Patients Using Antimicrobial Gel with Postbiotics, Lactoferrin, and Aloe Barbadensis Leaf Juice Powder vs. Conventional Chlorhexidine Gel: A Split-Mouth Randomized Clinical Trial.

Butera 2022 · Butera Andrea, Gallo Simone, Pascadopoli Maurizio, et al. · Antibiotics (Basel, Switzerland) · 2022

Included by

Natural Agents for the Improvement of Gingival Health: Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Non-Cochrane · intervention · 2026 · cited as Butera 2022 · Table 1; Figure 2; reference list
Outcome this study informsPooled effectEvidenceCertainty
Gingival health (bleeding on probing, or gingival index when BoP not reported)
Natural-ingredient toothpastes and gels (e.g., Aloe vera, Pudilan, hydroxyapatite, herbal extracts) vs Control toothpastes and gels (placebo or active control) · 12 weeks to 6 months
MD 0.63 [0.19, 1.07]10 studiesGRADE not reported

1 including review in total.