Primary study · included by 1 review

The association between periodontitis and cardiovascular risks in asymptomatic healthy patients.

Donders 2021 · Donders H C M, Veth E O, van 't Hof A W J, et al. · International journal of cardiology. Cardiovascular risk and prevention · 2021

Included by

Association between atherosclerosis and tooth loss in adult patients: systematic review and meta-analysis.

Non-Cochrane · aetiology · 2026 · cited as Donders 2021 · Table 1; Fig. 2; Fig. 3; Supplementary Table 4; references

Outcome this study informs	Pooled effect	Evidence	Certainty
Number of missing teeth Exposure: atherosclerosis (including peripheral arterial disease and carotid artery calcifications) vs Unexposed: low atherosclerotic burden	MD 5.07 [-10.30, 20.45]	2 studies	GRADE not reported
Number of missing teeth Exposure: atherosclerosis (including peripheral arterial disease and carotid artery calcifications) vs Unexposed: low atherosclerotic burden	MD 3.08 [1.80, 4.37]	8 studies	Very low
Number of missing teeth Exposure to atherosclerosis (diagnosed by angiography, CT, ultrasound, ABI or CBCT) vs No or low atherosclerotic burden (unexposed)	Meta-regression coefficient -0.115 [-0.42, 0.19]	8 studies	GRADE not reported
Number of missing teeth Exposure: atherosclerosis (including peripheral arterial disease and carotid artery calcifications) vs Unexposed: low atherosclerotic burden	MD 2.22 [-2.21, 6.66]	3 studies	GRADE not reported
Number of missing teeth Exposure: atherosclerosis (including peripheral arterial disease and carotid artery calcifications) vs Unexposed: low atherosclerotic burden	MD 3.08 [1.53, 4.64]	8 studies	Very low
Number of missing teeth Exposure: atherosclerosis (including peripheral arterial disease and carotid artery calcifications) vs Unexposed: low atherosclerotic burden	MD 2.16 [0.34, 3.97]	5 studies	GRADE not reported
Number of missing teeth Exposure: atherosclerosis (including peripheral arterial disease and carotid artery calcifications) vs Unexposed: low atherosclerotic burden	MD 5.07 [-10.30, 20.45]	2 studies	GRADE not reported
Number of missing teeth Exposure: atherosclerosis (including peripheral arterial disease and carotid artery calcifications) vs Unexposed: low atherosclerotic burden	MD 2.06 [-11.16, 15.27]	2 studies	GRADE not reported
Number of missing teeth Exposure to atherosclerosis (diagnosed by angiography, CT, ultrasound, ABI or CBCT) vs No or low atherosclerotic burden (unexposed)	Meta-regression coefficient 0.008 [-0.63, 0.65]	8 studies	GRADE not reported

1 including review in total.