Primary study · included by 1 review

Glass Ionomer Sealant versus Fluoride Varnish Application to Prevent Occlusal Caries in Primary Second Molars among Preschool Children: A Randomized Controlled Trial.

Lam 2021 · Ying Lam Phoebe Pui, Sardana Divesh, Luo Weijia, et al. · Caries research · 2021

Included by

Effectiveness of Fluoride Varnish Versus Conventional Glass Ionomer in Preventing Occlusal Caries: A Systematic Review and Meta-Analysis.
Non-Cochrane · intervention · 2026 · cited as Lam 2021 · Table 2; Figures 3-6; References
Outcome this study informsPooled effectEvidenceCertainty
Patient-reported anxiety and pain during application
Fluoride varnish (FV) vs Conventional glass ionomer cement (GIC) sealant · At application
RR 0.29 [0.04, 2.17]2 studies · 736 participantsLow
Incidence of occlusal caries involving dentin (ICDAS 4 or higher)
Fluoride varnish (FV) vs Conventional glass ionomer cement (GIC) sealant · 12 to 24 months follow-up
RR 0.98 [0.80, 1.21]4 studies · 3228 participantsModerate
Plaque accumulation (Visible Plaque Index, VPI)
Fluoride varnish (FV) vs Conventional glass ionomer cement (GIC) sealant
SMD 0.11 [0.01, 0.21]3 studies · 1472 participantsModerate
Caries of adjacent second molars
Fluoride varnish (FV) vs Conventional glass ionomer cement (GIC) sealant · 12 to 24 months follow-up
RR 0.99 [0.80, 1.23]3 studies · 2929 participantsLow

1 including review in total.