evidencegaps
Primary study · included by 1 review

Adjunctive use of metronidazole-minocycline ointment in the nonsurgical treatment of peri-implantitis: A multicenter randomized controlled trial.

Park 2021 · Park Seung-Hyun, Song Young Woo, Cha Jae-Kook, et al. · Clinical implant dentistry and related research · 2021

Included by

Risk-based efficacy of systemic and local antibiotics in nonsurgical treatment of peri-implantitis: A systematic review and meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Park 2021 · Table 1; reference 33
Outcome this study informsPooled effectEvidenceCertainty
Probing depth (PD) reduction
Systemic or local antibiotics adjunctive to nonsurgical debridement vs Nonsurgical mechanical debridement alone
SMD -0.666 [-1.014, -0.318]6 studies · 325 participantsGRADE not reported

1 including review in total.