Primary study · included by 1 review
Prognostic value of tertiary lymphoid structures in early clinical stage oral tongue squamous cell carcinoma.
Wang C 2021 · Wang Cheng, Huang Zhengxian, Zhang Ming, et al. · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2021
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Overall survival Absence of tertiary lymphoid structures (TLS-negative tumors) vs Presence of tertiary lymphoid structures (TLS-positive tumors, reference category) · Follow-up 24 to 120 months | HR 2.20 [1.74, 2.78] | 7 studies · 1465 participants | GRADE not reported |
Overall survival Absence of tertiary lymphoid structures (TLS-negative tumors) vs Presence of tertiary lymphoid structures (TLS-positive tumors, reference category) · Follow-up 24 to 120 months | HR 1.97 [1.42, 2.73] | 3 studies · 575 participants | GRADE not reported |
Disease-free survival Absence of tertiary lymphoid structures (TLS-negative tumors) vs Presence of tertiary lymphoid structures (TLS-positive tumors, reference category) · Follow-up 24 to 120 months | HR 2.21 [1.49, 3.28] | 3 studies · 453 participants | GRADE not reported |
1 including review in total.