evidencegaps
Primary study · included by 1 review

Vitamin E for the Prevention of Chemotherapy-Induced Peripheral Neuropathy: A meta-Analysis.

Chen 2021 · Chen Jie, Shan Haili, Yang Wenjun, et al. · Frontiers in pharmacology · 2021

Included by

The Efficacy and Safety of Nutritional Supplements for Cancer Supportive Care: An Umbrella Review and Hierarchical Evidence Synthesis.
Non-Cochrane · umbrella · 2026 · cited as Chen 2021 · Reference 69; Tables 2-8
Outcome this study informsPooled effectEvidenceCertainty
Chemotherapy-induced peripheral neuropathy incidence (all grades)
Vitamin E (300 to 600 mg/d) vs Not reported
RR 0.55 [0.36, 0.85]8 studies · 307 participantsVery low
Chemotherapy-induced peripheral neuropathy severity
Vitamin E (300 to 600 mg/d) vs Not reported
Severity CIPN: NS (3 RCTs, n = 262)3 studies · 262 participantsGRADE not reported

1 including review in total.