evidencegaps
Primary study · included by 2 reviews

Association between quality of life and patient-reported complications from surgery and radioiodine in early-stage thyroid cancer survivors: A matched-pair analysis.

Chow 2021 · Chow Kimberly Y, Kurumety Sasha, Helenowski Irene B, et al. · Surgery · 2021

Included by

Salivary and lacrimal disorders in patients treated with radioiodine for differentiated thyroid cancer.
Non-Cochrane · prognostic · 2026 · cited as Chow 2021 · Supplementary Table S3 (included studies); Figs. 1-3
Outcome this study informsPooled effectEvidenceCertainty
Xerostomia (pooled prevalence)
Radioiodine (I131) therapy · more than 1 year after RIT
Prevalence 0.17 [0.10, 0.28]6 studies · 1005 participantsGRADE not reported
Reassessing Radioactive Iodine Use After Thyroidectomy in Low-Risk Differentiated Thyroid Cancer: A Systematic Review and Meta-Analysis.
Non-Cochrane · intervention · 2026 · cited as Chow 2021 · Table 1; Fig. 3-8
Outcome this study informsPooled effectEvidenceCertainty
Xerostomia (adverse effect)
Radioactive iodine (RAI) ablation after total thyroidectomy vs No RAI (total thyroidectomy alone)
OR 5.63 [0.05, 667.24]2 studies · 748 participantsGRADE not reported
Dysphonia (adverse effect)
Radioactive iodine (RAI) ablation after total thyroidectomy vs No RAI (total thyroidectomy alone)
OR 0.96 [0.53, 1.72]2 studies · 748 participantsGRADE not reported

2 including reviews in total.