Primary study · included by 1 review
Impact of a toothpaste with microcrystalline hydroxyapatite on the occurrence of early childhood caries: a 1-year randomized clinical trial.
Paszynska 2021 · Paszynska Elzbieta, Pawinska Malgorzata, Gawriolek Maria, et al. · Scientific reports · 2021
PubMed 33514787doi:10.1038/s41598-021-81112-yJournal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Trial PICO
Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.
Results
Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Caries lesion initiation/progression (ICDAS score, laser fluorescence/DIAGNOdent, photographic pixels, enamel acid resistance) Fluoride-free nano-/micro-hydroxyapatite (nHA) dentifrice vs Fluoride-containing (fluoridated) dentifrice control · Median follow-up 6 months (range 6-12 months) | No meta-analysis was performed for the in vivo studies owing to high heterogeneity (population, control group, outcomes, follow-up periods, risk of bias) and differing statistical designs (e.g., non-inferiority);… | 5 studies · 420 participants | Ungraded |
1 including review in total.