Primary study · included by 1 review

Enamel demineralization during clear aligner orthodontic treatment compared with fixed appliance therapy, evaluated with quantitative light-induced fluorescence: A randomized clinical trial.

Albhaisi 2020 · Albhaisi Ziad, Al-Khateeb Susan N, Abu Alhaija Elham S · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics · 2020

PubMed 32354432 doi:10.1016/j.ajodo.2020.01.004Journal Article; Randomized Controlled Trial

Trial PICO

Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.

Results

Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.

Included by

White spot lesions, plaque accumulation and salivary caries-associated bacteria in clear aligners compared to fixed orthodontic treatment. A systematic review and meta- analysis.

Non-Cochrane · intervention · 2023 · cited as Albhaisi 2020 · Table 3; Ref [12] (Am J Orthod Dentofacial Orthop 2020, RCT); WSL incidence and severity (P1-O3, P1-O4)

Outcome this study informs	Pooled effect	Evidence	Certainty
Salivary caries-associated bacteria (S. mutans and Lactobacilli, subjects with >10^5 CFU/mL) Clear aligners (CA) vs Conventional fixed orthodontic appliances (CF) · 3 and 6 months	Not meta-analyzed (insufficient number of studies). Both included observational studies (Mummolo 2020 [19]; Mummolo 2020 [25]) reported a higher number of subjects with S. mutans and Lactobacilli >10^5 CFU/mL in the…	2 studies	Ungraded

1 including review in total.