Primary study · included by 2 reviews

Salivary levels of Streptococcus mutans and Lactobacilli and other salivary indices in patients wearing clear aligners versus fixed orthodontic appliances: An observational study.

Mummolo et al. 2020a · Mummolo Stefano, Nota Alessandro, Albani Francesca, et al. · PloS one · 2020

PubMed 32330172 doi:10.1371/journal.pone.0228798Comparative Study; Journal Article; Observational Study

Trial PICO

Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.

Results

Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.

Included by

Impact of Aligners and Fixed Appliances on Oral Health during Orthodontic Treatment: A Systematic Review and Meta-Analysis.

Non-Cochrane · intervention · 2021 · cited as Mummolo et al. 2020a · Table 1; Table 5 (Adults, S. mutans/lactobacilli 3-6 months); Reference 39

Outcome this study informs	Pooled effect	Evidence	Certainty
S. mutans presence (CFU > 10^5) Clear aligners (Invisalign / thermoformed aligners) vs Fixed appliances · 3 months	RR 0.07 [0.01, 0.49]	2 studies · 140 participants	Low

White spot lesions, plaque accumulation and salivary caries-associated bacteria in clear aligners compared to fixed orthodontic treatment. A systematic review and meta- analysis.

Non-Cochrane · intervention · 2023 · cited as Mummolo 2020 [19] · Tables 4 and 5; Ref [19] (PLoS ONE 2020, prospective cohort); SCB (P1-O2) and plaque meta-analysis (P1-O1, Figs 4/5/6)

The review does not say which of its outcomes this study informs.

2 including reviews in total.