Primary study · included by 1 review

A Randomized Control Trial Comparing Buccal Infiltration of 4% Articaine with Buccal and Palatal Infiltration of 2% Lignocaine for the Extraction of Maxillary Premolar Teeth.

Sandilya 2019 · Sandilya Vikas, Andrade Neelam Noel, Mathai Paul C, et al. · Contemporary clinical dentistry · 2019

Included by

Efficacy comparison of articaine versus lidocaine in dental anesthesia: a meta-analysis of randomized controlled trials.
Non-Cochrane · intervention · 2026 · cited as Andrade 2019 · Reference 13; Results (studies cited per outcome); Table 1
Outcome this study informsPooled effectEvidenceCertainty
Anesthetic onset time (min)
4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia
MD -1.81 [-2.85, -0.78]5 studiesGRADE not reported
Anesthetic onset time (min)
4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia
MD -0.57 [-0.99, -0.16]2 studiesGRADE not reported
Anesthetic onset time
4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia
MD -1.34 [-2.21, -0.47]7 studies · 705 participantsLow
Anesthetic onset time (min)
4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia
MD -2.2 [-3.36, -1.03]3 studiesGRADE not reported
Anesthetic onset time (min)
4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia
MD -0.59 [-2.12, 0.95]4 studiesGRADE not reported

1 including review in total.