Primary study · included by 1 review

Safety and Efficacy of RimabotulinumtoxinB for Treatment of Sialorrhea in Adults: A Randomized Clinical Trial.

Isaacson 2020 · Isaacson Stuart H, Ondo William, Jackson Carlayne E, et al. · JAMA neurology · 2020

PubMed 31930364 doi:10.1001/jamaneurol.2019.4565Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Trial PICO

Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.

Results

Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.

Included by

Oral health effects of botulinum toxin treatment for drooling: a systematic review.

Non-Cochrane · intervention · 2021 · cited as Isaacson 2020 · References [2]; Results (Carious lesions); Table 1 (RCT; also registered as NCT01994109)

Outcome this study informs	Pooled effect	Evidence	Certainty
New dental caries development Intraglandular botulinum neurotoxin (BoNT) injection vs No BoNT (placebo or pre-treatment baseline)	RR 2.4 [0.48, 11.80]	1 study	Ungraded
New dental caries development Intraglandular botulinum neurotoxin (BoNT) injection vs No BoNT (placebo or pre-treatment baseline)	RR 1.4 [0.24, 8.12]	1 study	Ungraded

1 including review in total.