Primary study · included by 1 review

Injectable platelet-rich fibrin and microneedling for gingival augmentation in thin periodontal phenotype: A randomized controlled clinical trial.

Ozsagir et al., 2020 · Ozsagir Zeliha Betul, Saglam Ebru, Sen Yilmaz Berza, et al. · Journal of clinical periodontology · 2020

Included by

Efficacy of injectable platelet-rich fibrin and microneedling for thin gingival phenotype: a systematic review and meta-analysis.

Non-Cochrane · intervention · 2026 · cited as Ozsagir 2020 · Table 2; References; Figs. 4-7

Outcome this study informs	Pooled effect	Evidence	Certainty
Gingival thickness Injectable platelet-rich fibrin vs Baseline before i-PRF · Baseline to 6 months	MD 0.17 [0.12, 0.22]	2 studies · 65 participants	Low
Keratinized tissue width Injectable platelet-rich fibrin plus microneedling vs Injectable platelet-rich fibrin · 6 months	MD 0.04 [-0.30, 0.37]	2 studies · 65 participants	Low
Gingival thickness Injectable platelet-rich fibrin plus microneedling vs Injectable platelet-rich fibrin · 1, 3 and 6 months pooled	MD 0.05 [0.02, 0.08]	3 studies	GRADE not reported
Keratinized tissue width Injectable platelet-rich fibrin plus microneedling vs Baseline before i-PRF plus microneedling · Baseline to 6 months	MD 0.43 [-0.24, 1.10]	2 studies · 65 participants	Low
Gingival thickness Injectable platelet-rich fibrin plus microneedling vs Injectable platelet-rich fibrin · 1 month	MD 0.02 [-0.03, 0.06]	2 studies · 69 participants	Low
Gingival thickness Injectable platelet-rich fibrin plus microneedling vs Baseline before i-PRF plus microneedling · Baseline to 6 months	MD 0.26 [0.20, 0.31]	2 studies · 65 participants	Low
Keratinized tissue width (KTW, mm) Injectable platelet-rich fibrin plus microneedling (i-PRF + MN) vs Injectable platelet-rich fibrin (i-PRF) alone · 3 months	MD 0.04 [-0.29, 0.37]	2 studies · 65 participants	Low
Gingival thickness (GT, mm) Injectable platelet-rich fibrin plus microneedling (i-PRF + MN) vs Injectable platelet-rich fibrin (i-PRF) alone · 3 months	MD 0.05 [0.01, 0.09]	3 studies · 101 participants	Low
Gingival thickness Injectable platelet-rich fibrin plus microneedling vs Microneedling	no estimate extracted	1 study	GRADE not reported
Keratinized tissue width Injectable platelet-rich fibrin plus microneedling vs Injectable platelet-rich fibrin · 3 and 6 months pooled	MD 0.04 [-0.20, 0.27]	2 studies	GRADE not reported
Keratinized tissue width Injectable platelet-rich fibrin vs Baseline before i-PRF · Baseline to 6 months	MD 0.39 [-0.29, 1.07]	2 studies · 65 participants	Low
Gingival thickness Injectable platelet-rich fibrin plus microneedling vs Injectable platelet-rich fibrin · 6 months	MD 0.10 [-0.03, 0.24]	2 studies · 65 participants	Low
Keratinized tissue width Injectable platelet-rich fibrin plus microneedling vs Microneedling	no estimate extracted	1 study	GRADE not reported

1 including review in total.