Primary study · included by 1 review

Regenerative Endodontic Procedures in Necrotic Mature Teeth with Periapical Radiolucencies: A Preliminary Randomized Clinical Study.

Arslan 2019 · Arslan Hakan, Ahmed Hany Mohamed Aly, Şahin Yavuz, et al. · Journal of endodontics · 2019

Included by

Association of Apical Maturity With Clinical and Biological Outcomes After Regenerative Endodontic Procedures: A Systematic Review and Meta-Analysis.

Non-Cochrane · intervention · 2026 · cited as Arslan 2019 · Table 1; reference list

Outcome this study informs	Pooled effect	Evidence	Certainty
Tooth survival rate Regenerative endodontic procedures (blood clot, PRF, CaOH, TAP, MTA, FGF and others) vs None (single-arm proportions pooled across study arms) · Follow-up 12 to 52 months	Proportion 0.98 [0.96, 0.99]	9 studies · 453 participants	GRADE not reported
Pulp vitality recovery rate Regenerative endodontic procedures (blood clot, PRF, CaOH, TAP, MTA, FGF and others) vs None (single-arm proportions pooled across study arms) · Follow-up 12 to 52 months	Proportion 0.21 [0.07, 0.49]	4 studies · 224 participants	GRADE not reported
Pulp vitality recovery rate Regenerative endodontic procedures (blood clot, PRF, CaOH, TAP, MTA, FGF and others) vs None (single-arm proportions pooled across study arms) · Follow-up 12 to 52 months	Proportion 0.32 [0.26, 0.39]	4 studies · 224 participants	GRADE not reported
Tooth survival rate Regenerative endodontic procedures (blood clot, PRF, CaOH, TAP, MTA, FGF and others) vs None (single-arm proportions pooled across study arms) · Follow-up 12 to 52 months	Proportion 0.98 [0.95, 0.99]	9 studies · 453 participants	GRADE not reported
Clinical success rate Regenerative endodontic procedures (blood clot, PRF, CaOH, TAP, MTA, FGF and others) vs None (single-arm proportions pooled across study arms) · Follow-up 12 to 52 months	Proportion 0.90 [0.83, 0.95]	10 studies · 496 participants	GRADE not reported
Clinical success rate Regenerative endodontic procedures (blood clot, PRF, CaOH, TAP, MTA, FGF and others) vs None (single-arm proportions pooled across study arms) · Follow-up 12 to 52 months	Proportion 0.89 [0.86, 0.91]	10 studies · 496 participants	GRADE not reported

1 including review in total.