Primary study · included by 1 review
Impact of a non-fluoridated microcrystalline hydroxyapatite dentifrice on enamel caries progression in highly caries-susceptible orthodontic patients: A randomized, controlled 6-month trial.
Schlagenhauf 2019 · Schlagenhauf Ulrich, Kunzelmann Karl-Heinz, Hannig Christian, et al. · Journal of investigative and clinical dentistry · 2019
Trial PICO
Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.
Results
Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Caries lesion initiation/progression (ICDAS score, laser fluorescence/DIAGNOdent, photographic pixels, enamel acid resistance) Fluoride-free nano-/micro-hydroxyapatite (nHA) dentifrice vs Fluoride-containing (fluoridated) dentifrice control · Median follow-up 6 months (range 6-12 months) | No meta-analysis was performed for the in vivo studies owing to high heterogeneity (population, control group, outcomes, follow-up periods, risk of bias) and differing statistical designs (e.g., non-inferiority);… | 5 studies · 420 participants | Ungraded |
1 including review in total.