Primary study · included by 1 review

Systemic corticosteroids may be beneficial for managing severe or refractory orbital cellulitis in children.

Brameli 2018 · Brameli Anna, Ashkenazi-Hoffnung Liat, Giloni Dror, et al. · Acta paediatrica (Oslo, Norway : 1992) · 2018

Included by

Clinical Outcomes of Adjunctive Corticosteroid Therapy Versus Standard Treatment Alone in Patients With Bacterial Facial Infections: A Systematic Review and Meta-Analysis.

Non-Cochrane · intervention · 2026 · cited as Brameli 2018 · Table 1; Figure 3; Figure 4; Table S2

Outcome this study informs	Pooled effect	Evidence	Certainty
Pre-treatment C-reactive protein (CRP) Adjunctive oral or intravenous corticosteroids plus standard treatment vs Standard treatment alone (antibiotics, NSAIDs or no steroids) · Pre-treatment	SMD 0.33 [0.09, 0.58]	3 studies · 1271 participants	Low
Hospital stay (days) Adjunctive oral or intravenous corticosteroids plus standard treatment vs Standard treatment alone (antibiotics, NSAIDs or no steroids) · At discharge	MD -1.87 [-5.90, 2.16]	3 studies	GRADE not reported
Hospital stay (days) Adjunctive oral or intravenous corticosteroids plus standard treatment vs Standard treatment alone (antibiotics, NSAIDs or no steroids) · At discharge	MD -2.65 [-6.23, 0.91]	4 studies	GRADE not reported
Hospital stay (days) Adjunctive oral or intravenous corticosteroids plus standard treatment vs Standard treatment alone (antibiotics, NSAIDs or no steroids) · At discharge	MD -0.93 [-4.14, 2.27]	4 studies	GRADE not reported
Hospital stay (days) Adjunctive oral or intravenous corticosteroids plus standard treatment vs Standard treatment alone (antibiotics, NSAIDs or no steroids) · At discharge	MD -1.63 [-3.55, 0.28]	8 studies	GRADE not reported
Hospital stay (days) Adjunctive oral or intravenous corticosteroids plus standard treatment vs Standard treatment alone (antibiotics, NSAIDs or no steroids) · At discharge	MD -0.77 [-2.68, 1.15]	6 studies	GRADE not reported
Hospital stay (days) Adjunctive oral or intravenous corticosteroids plus standard treatment vs Standard treatment alone (antibiotics, NSAIDs or no steroids) · At discharge	MD -1.61 [-3.17, -0.05]	10 studies · 13058 participants	Low
Hospital stay (days) Adjunctive oral or intravenous corticosteroids plus standard treatment vs Standard treatment alone (antibiotics, NSAIDs or no steroids) · At discharge	MD -1.32 [-30.48, 27.85]	2 studies	GRADE not reported
Hospital stay (days) Adjunctive oral or intravenous corticosteroids plus standard treatment vs Standard treatment alone (antibiotics, NSAIDs) or no steroids · Until discharge	MD -5.75 [-8.19, -3.31]	1 study	GRADE not reported
Hospital stay (days) Adjunctive oral or intravenous corticosteroids plus standard treatment vs Standard treatment alone (antibiotics, NSAIDs or no steroids) · At discharge	MD -1.65 [-23.09, 19.81]	2 studies	GRADE not reported

1 including review in total.