Primary study · included by 1 review
Effect of local application of curcumin and ornidazole gel in chronic periodontitis patients.
Ravishankar 2017 · Ravishankar P L, Kumar Y Pradeep, Anila E N, et al. · International journal of pharmaceutical investigation · 2017
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Probing pocket depth (PPD) reduction, mean difference in mm (negative favors curcumin) Subgingivally delivered curcumin/turmeric-derived formulation (gel, chip, strip, in situ gel, nanoparticle) adjunctive to SRP vs Active comparator adjunct with SRP (chlorhexidine, ornidazole or other local agent) · Longest available follow-up | MD -0.68 [-1.38, 0.02] | 5 studies | Very low |
Probing pocket depth (PPD) reduction, mean difference in mm (negative favors curcumin) Subgingivally delivered curcumin/turmeric-derived formulation (gel, chip, strip, in situ gel, nanoparticle) adjunctive to SRP vs Inactive control (SRP alone, placebo or empty vehicle) · Longest available follow-up | MD -0.82 [-1.22, -0.42] | 8 studies | GRADE not reported |
1 including review in total.