Primary study · included by 1 review

Safety and Efficacy of Mesenchymal Stem Cells for Radiation-Induced Xerostomia: A Randomized, Placebo-Controlled Phase 1/2 Trial (MESRIX).

Gronhoj 2018 · Grønhøj Christian, Jensen David H, Vester-Glowinski Peter, et al. · International journal of radiation oncology, biology, physics · 2018

Included by

Treatment of Xerostomia with Mesenchymal Stem Cells - A Systematic Review and Meta-Analysis of Clinical Trials.
Non-Cochrane · intervention · 2026 · cited as Grønhøj 2018 (MESRIX) · Results, Table 1; reference 22
Outcome this study informsPooled effectEvidenceCertainty
Unstimulated whole salivary flow rate (UWS)
Mesenchymal stem cell (MSC) injection into the salivary glands vs Placebo (saline, saline with albumin, or DMSO) · Short term (up to 6 months; time point closest to 4 months)
MD 0.06 [-0.05, 0.17]3 studies · 214 participantsGRADE not reported

1 including review in total.