Primary study · included by 1 review
A clinicoradiographic assessment of 1% metformin gel with platelet-rich fibrin in the treatment of mandibular grade II furcation defects.
Sharma 2017 · Sharma Parul, Grover Harpreet Singh, Masamatti Sujata Surendra, et al. · Journal of Indian Society of Periodontology · 2017
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Bone fill (BF) Metformin (MF) plus PRF vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined) | SMD 2.29 | NR | GRADE not reported |
Clinical attachment level (CAL) gain Metformin (MF) plus PRF vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined) | SMD 1.91 | NR | GRADE not reported |
Clinical attachment level (CAL) gain Metformin (MF) plus PRF vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined) | SMD 0.99 | NR | GRADE not reported |
Clinical attachment level (CAL) gain Metformin (MF) plus PRF vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined) | SMD 1.91 [1.37, 2.46] | 4 studies | GRADE not reported |
Bone fill (BF) Metformin (MF) plus PRF vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined) | SMD 2.29 [2.15, 2.44] | 4 studies | GRADE not reported |
Bone fill (BF) Metformin (MF) plus PRF vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined) | SMD 2.07 | NR | GRADE not reported |
1 including review in total.