Primary study · included by 1 review

Relationship between dental status and development of osteoradionecrosis of the jaw: a multicenter retrospective study.

Kojima 2017 · Kojima Yuka, Yanamoto Souichi, Umeda Masahiro, et al. · Oral surgery, oral medicine, oral pathology and oral radiology · 2017

Included by

Periodontal Disease and Risk of Osteoradionecrosis in Patients with Head and Neck Cancer Undergoing Radiotherapy: A Systematic Review and Meta-Analysis.

Non-Cochrane · prognostic · 2026 · cited as Kojima 2017 · ref 29; Table 1

Outcome this study informs	Pooled effect	Evidence	Certainty
Osteoradionecrosis of the jaws Periodontal disease or poor periodontal status (exposure) vs No periodontal disease, healthy or mild periodontal status	Pooled relative effect estimate (HR/OR/RR) 6.77 [2.65, 17.32]	5 studies	GRADE not reported
Osteoradionecrosis of the jaws Periodontal disease or poor periodontal status (exposure) vs No periodontal disease, healthy or mild periodontal status	Pooled relative effect estimate (HR/OR/RR) 4.83 [1.96, 11.93]	6 studies	GRADE not reported
Osteoradionecrosis of the jaws Periodontal disease or poor periodontal status (exposure) vs No periodontal disease, healthy or mild periodontal status	Pooled relative effect estimate (HR/OR/RR) 4.82 [1.50, 15.51]	6 studies	GRADE not reported
Prevalence of osteoradionecrosis of the jaws Radiotherapy for head and neck cancer	Pooled prevalence 0.09 [0.06, 0.13]	7 studies · 1785 participants	GRADE not reported
Osteoradionecrosis of the jaws Periodontal disease or poor periodontal status (exposure) vs No periodontal disease, healthy or mild periodontal status	Pooled relative effect estimate (HR/OR/RR) 4.55 [1.63, 12.69]	5 studies	GRADE not reported
Osteoradionecrosis of the jaws Periodontal disease or poor periodontal status (exposure) vs No periodontal disease, healthy or mild periodontal status	Pooled relative effect estimate (HR/OR/RR) 3.80 [1.45, 9.97]	5 studies	GRADE not reported
Osteoradionecrosis of the jaws Periodontal disease or poor periodontal status (exposure) vs No periodontal disease, healthy or mild periodontal status	Pooled relative effect estimate (HR/OR/RR) 3.94 [1.66, 9.35]	5 studies	GRADE not reported
Osteoradionecrosis of the jaws Periodontal disease or poor periodontal status (exposure) vs No periodontal disease, healthy or mild periodontal status	Pooled relative effect estimate (HR/OR/RR) 6.03 [2.32, 15.67]	5 studies	GRADE not reported
Osteoradionecrosis of the jaws Periodontal disease or poor periodontal status (exposure) vs No periodontal disease, healthy or mild periodontal status	Pooled relative effect estimate (HR/OR/RR) 4.81 [1.59, 14.55]	5 studies	GRADE not reported

1 including review in total.