Primary study · included by 2 reviews

Comparative Evaluation of Anesthetic Efficacy of 2% Lidocaine, 4% Articaine, and 0.5% Bupivacaine on Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Clinical Trial.

Aggarwal 2017 · Aggarwal Vivek, Singla Mamta, Miglani Sanjay · Journal of oral & facial pain and headache · 2017

Included by

Efficacy comparison of articaine versus lidocaine in dental anesthesia: a meta-analysis of randomized controlled trials.

Non-Cochrane · intervention · 2026 · cited as Aggarwal 2017 · Reference 30; Results (studies cited per outcome); Table 1

Outcome this study informs	Pooled effect	Evidence	Certainty
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.07 [0.88, 1.31]	5 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.0 [0.69, 1.46]	3 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.05 [0.91, 1.21]	6 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.09 [0.82, 1.43]	5 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.37 [0.78, 2.41]	3 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.06 [0.90, 1.24]	9 studies · 683 participants	Low
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.03 [0.88, 1.2]	4 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.03 [0.78, 1.35]	3 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 0.95 [0.8, 1.14]	4 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 0.85 [0.69, 1.04]	3 studies	GRADE not reported

Comparative efficacy and safety of bupivacaine versus articaine in third molar surgery: a systematic review and meta-analysis of randomized controlled trials.

Non-Cochrane · 2026 · cited as Aggarwal 2017 · Table 1; reference 9

The review does not say which of its outcomes this study informs.

2 including reviews in total.