Primary study · included by 1 review
Topical 5-Fluorouracil is a Novel Targeted Therapy for the Keratocystic Odontogenic Tumor.
Ledderhof 2017 · Ledderhof Nicholas J, Caminiti Marco F, Bradley Grace, et al. · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · 2017
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Recurrence 5-FU (5% topical) after enucleation and peripheral ostectomy vs Modified Carnoy's solution (MCS) after enucleation and peripheral ostectomy · Follow-up 12 to 108 months across studies | RD -0.199 [-0.283, -0.114] | 5 studies · 181 participants | Moderate |
Postoperative paresthesia (any) 5-FU (5% topical) after enucleation and peripheral ostectomy vs Modified Carnoy's solution (MCS) after enucleation and peripheral ostectomy · Follow-up 12 to 108 months across studies | RD -0.158 [-0.281, -0.035] | 5 studies · 181 participants | Moderate |
Permanent paresthesia 5-FU (5% topical) after enucleation and peripheral ostectomy vs Modified Carnoy's solution (MCS) after enucleation and peripheral ostectomy · Follow-up 12 to 108 months across studies | RD -0.061 [-0.14, 0.018] | 5 studies · 181 participants | GRADE not reported |
1 including review in total.