Primary study · included by 1 review

Mandibular Degree II Furcation Defects Treatment With Platelet-Rich Fibrin and 1% Alendronate Gel Combination: A Randomized Controlled Clinical Trial.

Kanoriya 2016b · Kanoriya Dharmendra, Pradeep A R, Garg Vibhuti, et al. · Journal of periodontology · 2017

Included by

Outcome this study informsPooled effectEvidenceCertainty
Bone fill (BF)
Alendronate (ALN) plus platelet-rich fibrin (PRF) vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined)
SMD 2.45NRGRADE not reported
Clinical attachment level (CAL) gain
Alendronate (ALN) plus platelet-rich fibrin (PRF) vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined)
SMD 1.89NRGRADE not reported
Bone fill (BF)
Alendronate (ALN) plus platelet-rich fibrin (PRF) vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined)
SMD 2.32NRGRADE not reported
Bone fill (BF)
Alendronate (ALN) plus platelet-rich fibrin (PRF) vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined)
SMD 2.45 [2.34, 2.56]3 studiesGRADE not reported
Clinical attachment level (CAL) gain
Alendronate (ALN) plus platelet-rich fibrin (PRF) vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined)
SMD 1.89 [1.57, 2.21]3 studiesGRADE not reported
Clinical attachment level (CAL) gain
Alendronate (ALN) plus platelet-rich fibrin (PRF) vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined)
SMD 0.99NRGRADE not reported

1 including review in total.