Primary study · included by 1 review

Anesthetic Efficacy in Irreversible Pulpitis: A Randomized Clinical Trial.

Allegretti 2016 · Allegretti Carlos E, Sampaio Roberta M, Horliana Anna C R T, et al. · Brazilian dental journal · 2016

Included by

Efficacy comparison of articaine versus lidocaine in dental anesthesia: a meta-analysis of randomized controlled trials.

Non-Cochrane · intervention · 2026 · cited as Allegretti 2016 · Reference 32; Results (studies cited per outcome); Table 1

Outcome this study informs	Pooled effect	Evidence	Certainty
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.07 [0.88, 1.31]	5 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.0 [0.69, 1.46]	3 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.05 [0.91, 1.21]	6 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.09 [0.82, 1.43]	5 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.37 [0.78, 2.41]	3 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.06 [0.90, 1.24]	9 studies · 683 participants	Low
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.03 [0.88, 1.2]	4 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 1.03 [0.78, 1.35]	3 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 0.95 [0.8, 1.14]	4 studies	GRADE not reported
Anesthetic success rate 4% articaine with epinephrine, nerve block anesthesia vs 2% lidocaine with epinephrine, nerve block anesthesia	RR 0.85 [0.69, 1.04]	3 studies	GRADE not reported

1 including review in total.