Primary study · included by 1 review

Oral microflora and selection of resistance after a single dose of amoxicillin.

Khalil 2016 · Khalil D, Hultin M, Rashid M U, et al. · Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2016

Included by

Perioperative Antimicrobial Prophylaxis for Invasive Dental Procedures: A Systematic Review and Random-Effects Meta-Analysis of Randomized and Placebo-Controlled Studies.

Non-Cochrane · intervention · 2026 · cited as Khalil 2016 · Table 1; Figures 2-4

Outcome this study informs	Pooled effect	Evidence	Certainty
Secondary continuous postoperative outcome (postoperative morbidity indicator, not further specified) Perioperative antimicrobial/antibiotic prophylaxis (systemic antibiotics and/or local antiseptic) vs Placebo or no prophylaxis · Postoperative	MD 0.02 [-0.38, 0.42]	5 studies · 596 participants	GRADE not reported
Primary pooled endpoint: procedure-related bacteremia or early infectious outcome (event proportion on a 0-1 scale entered as mean) Perioperative antimicrobial/antibiotic prophylaxis (systemic antibiotics and/or local antiseptic) vs Placebo or no prophylaxis · Early perioperative	MD -0.17 [-0.45, 0.11]	8 studies · 1407 participants	GRADE not reported
Primary pooled endpoint: procedure-related bacteremia or early infectious outcome (event proportion on a 0-1 scale entered as mean) Perioperative antimicrobial/antibiotic prophylaxis (systemic antibiotics and/or local antiseptic) vs Placebo or no prophylaxis · Early perioperative	MD -0.12 [-0.31, 0.07]	10 studies · 1950 participants	GRADE not reported

1 including review in total.