Primary study · included by 1 review

Efficacy of Subgingivally Delivered 1.2% Atorvastatin in the Treatment of Chronic Periodontitis in Patients With Type 2 Diabetes Mellitus: A Randomized Controlled Clinical Trial.

Kumari 2016 · Kumari Minal, Martande Santosh S, Pradeep A R, et al. · Journal of periodontology · 2016

Included by

Adjunctive Use of Locally Delivered Statins in Periodontal Therapy and Pre-Implant Bone Regeneration: A Systematic Review and Meta-Analysis.
Non-Cochrane · intervention · 2026 · cited as Kumari 2016 · Figures 2-4; Tables 4-5 and reference list
Outcome this study informsPooled effectEvidenceCertainty
Clinical attachment level (CAL), change from baseline (mm)
SRP plus locally delivered 1.2% atorvastatin gel vs SRP alone (placebo gel or no gel) · 6 months
MD 1.70 [1.22, 2.19]6 studies · 332 participantsGRADE not reported
Probing pocket depth (PPD), change from baseline (mm)
SRP plus locally delivered 1.2% atorvastatin gel vs SRP alone (placebo gel or no gel) · 6 months
MD 1.39 [0.99, 1.79]6 studies · 332 participantsGRADE not reported

1 including review in total.