Primary study · included by 1 review

Effect of Oral Premedication on the Efficacy of Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Double-Blind, Randomized Controlled Clinical Trial.

Saha 2016 · Saha Suparna Ganguly, Jain Sohini, Dubey Sandeep, et al. · Journal of clinical and diagnostic research : JCDR · 2016

Included by

Outcome this study informsPooled effectEvidenceCertainty
Pain-free initial IANB success without supplemental anesthesia
Any oral NSAID before IANB vs Oral placebo before IANB · Intraoperative assessment, procedural steps vary by trial
RR 2.27 [1.81, 2.85]6 studies · 510 participantsGRADE not reported
Pain-free IANB success (no intraoperative pain at any recorded step after initial IANB and no supplemental anesthesia)
Oral NSAID premedication (any agent) + IANB vs Oral placebo + IANB · Intraoperative, after initial IANB (access and/or instrumentation or pulp extirpation)
RR 2.31 [1.89, 2.83]10 studiesGRADE not reported
Pain-free initial IANB success without supplemental anesthesia
Any oral NSAID before IANB vs Oral placebo before IANB · Intraoperative assessment, procedural steps vary by trial
RR 2.06 [1.48, 2.86]11 studies · 737 participantsLow
Pain-free initial IANB success without supplemental anesthesia
Any oral NSAID before IANB vs Oral placebo before IANB · Intraoperative assessment, procedural steps vary by trial
RR 2.28 [1.84, 2.82]7 studies · 576 participantsGRADE not reported
Pain-free IANB success (no intraoperative pain at any recorded step after initial IANB and no supplemental anesthesia)
Oral NSAID premedication (any agent) + IANB vs Oral placebo + IANB · Intraoperative, after initial IANB (access and/or instrumentation or pulp extirpation)
RR 2.01 [1.44, 2.81]10 studiesGRADE not reported

1 including review in total.