evidencegaps
Primary study · included by 1 review

Subgingivally delivered 1.2% atorvastatin in the treatment of chronic periodontitis among smokers: a randomized, controlled clinical trial.

Kumari 2017 · Kumari Minal, Martande Santosh S, Pradeep Avani R · Journal of investigative and clinical dentistry · 2017

Included by

Adjunctive Use of Locally Delivered Statins in Periodontal Therapy and Pre-Implant Bone Regeneration: A Systematic Review and Meta-Analysis.
Non-Cochrane · intervention · 2026 · cited as Kumari 2017 · Figures 2-4; Tables 4-5 and reference list
Outcome this study informsPooled effectEvidenceCertainty
Clinical attachment level (CAL), change from baseline (mm)
SRP plus locally delivered 1.2% atorvastatin gel vs SRP alone (placebo gel or no gel) · 6 months
MD 1.70 [1.22, 2.19]6 studies · 332 participantsGRADE not reported
Probing pocket depth (PPD), change from baseline (mm)
SRP plus locally delivered 1.2% atorvastatin gel vs SRP alone (placebo gel or no gel) · 6 months
MD 1.39 [0.99, 1.79]6 studies · 332 participantsGRADE not reported

1 including review in total.