evidencegaps
Primary study · included by 1 review

Autoantibody Profile of a Cohort of 78 Italian Patients with Mucous Membrane Pemphigoid: Correlation Between Reactivity Profile and Clinical Involvement.

Cozzani 2016 · Cozzani Emanuele, Di Zenzo Giovanni, Calabresi Valentina, et al. · Acta dermato-venereologica · 2016

Included by

Diagnostic Agreement in Subepidermal Blistering Diseases: Is ELISA Test Reliable as Direct Immunofluorescence? A Systematic Review, Meta-Analysis, and Trial Sequential Analysis.
Non-Cochrane · DTA · 2026 · cited as Cozzani 2016 · Table 2; References
Outcome this study informsPooled effectEvidenceCertainty
Diagnostic agreement between ELISA and DIF (risk difference in test positivity)
ELISA (BP180, BP230 and/or Lam332) in mucous membrane pemphigoid (index test) vs Direct immunofluorescence (DIF, reference standard) · At first diagnosis, before immunosuppressive therapy
RD 0.55 [0.43, 0.67]7 studies · 489 participantsGRADE not reported
Diagnostic agreement between ELISA and DIF (risk difference in test positivity)
ELISA for BP180 autoantibodies (index test) vs Direct immunofluorescence (DIF, reference standard) · At first diagnosis, before immunosuppressive therapy
RD 0.26 [0.19, 0.33]35 studies · 2776 participantsGRADE not reported
Diagnostic agreement between ELISA and DIF (risk difference in test positivity)
ELISA for BP230 autoantibodies (index test) vs Direct immunofluorescence (DIF, reference standard) · At first diagnosis, before immunosuppressive therapy
RD 0.59 [0.47, 0.71]27 studies · 2097 participantsGRADE not reported

1 including review in total.