Primary study · included by 2 reviews

Periodontal health status in patients treated with the Invisalign(®) system and fixed orthodontic appliances: A 3 months clinical and microbiological evaluation.

Levrini et al. 2015 · Levrini Luca, Mangano Alessandro, Montanari Paola, et al. · European journal of dentistry · 2015

PubMed 26430371 doi:10.4103/1305-7456.163218Journal Article

Trial PICO

Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.

Results

Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.

Included by

Impact of Aligners and Fixed Appliances on Oral Health during Orthodontic Treatment: A Systematic Review and Meta-Analysis.

Non-Cochrane · intervention · 2021 · cited as Levrini et al. 2015 · Table 1 (qualitative synthesis); Reference 31

The review does not say which of its outcomes this study informs.

White spot lesions, plaque accumulation and salivary caries-associated bacteria in clear aligners compared to fixed orthodontic treatment. A systematic review and meta- analysis.

Non-Cochrane · intervention · 2023 · cited as Levrini 2015 · Table 4; Ref [28] (Eur J Dent 2015, prospective cohort); plaque (P1-O1; no data available, not meta-analyzed)

Outcome this study informs	Pooled effect	Evidence	Certainty
Plaque accumulation (Plaque Index) Clear aligners (CA) vs Conventional fixed orthodontic appliances (CF) · Range 1 to 18 months (maximum time-point per study)	SMD -1.79 [-3.63, 0.04]	3 studies · 111 participants	Moderate
Plaque accumulation (Plaque Index) Clear aligners (CA) vs Conventional fixed orthodontic appliances (CF) · 6 months	SMD -2.04 [-3.37, -0.70]	5 studies · 253 participants	Ungraded
Plaque accumulation (Plaque Index) Clear aligners (CA) vs Conventional fixed orthodontic appliances (CF) · Range 1 to 12 months (maximum time-point per study)	SMD -1.46 [-2.77, -0.15]	5 studies · 246 participants	Moderate
Plaque accumulation (Plaque Index) Clear aligners (CA) vs Conventional fixed orthodontic appliances (CF) · 3 months	SMD -1.08 [-1.93, -0.24]	5 studies · 211 participants	Ungraded
Plaque accumulation (Plaque Index) Clear aligners (CA) vs Conventional fixed orthodontic appliances (CF) · Maximum reported time-point per study (range 1-18 months)	SMD -1.58 [-2.57, -0.58]	8 studies · 357 participants	Ungraded
Plaque accumulation (Plaque Index) Clear aligners (CA) vs Conventional fixed orthodontic appliances (CF) · 12 months	SMD -2.14 [-3.64, -0.64]	3 studies · 113 participants	Ungraded

2 including reviews in total.