Primary study · included by 1 review

Post-tooth extraction bacteraemia: a randomized clinical trial on the efficacy of chlorhexidine prophylaxis.

Barbosa 2015 · Barbosa Mario, Prada-López Isabel, Álvarez Maximiliano, et al. · PloS one · 2015

Included by

Perioperative Antimicrobial Prophylaxis for Invasive Dental Procedures: A Systematic Review and Random-Effects Meta-Analysis of Randomized and Placebo-Controlled Studies.

Non-Cochrane · intervention · 2026 · cited as Barbosa 2015 · Table 1; Figures 2-4

Outcome this study informs	Pooled effect	Evidence	Certainty
Primary pooled endpoint: procedure-related bacteremia or early infectious outcome (event proportion on a 0-1 scale entered as mean) Perioperative antimicrobial/antibiotic prophylaxis (systemic antibiotics and/or local antiseptic) vs Placebo or no prophylaxis · Early perioperative	MD -0.17 [-0.45, 0.11]	8 studies · 1407 participants	GRADE not reported
Primary pooled endpoint: procedure-related bacteremia or early infectious outcome (event proportion on a 0-1 scale entered as mean) Perioperative antimicrobial/antibiotic prophylaxis (systemic antibiotics and/or local antiseptic) vs Placebo or no prophylaxis · Early perioperative	MD -0.12 [-0.31, 0.07]	10 studies · 1950 participants	GRADE not reported

1 including review in total.