Primary study · included by 1 review
Polaprezinc reduces the severity of radiation-induced mucositis in head and neck cancer patients.
Doi 2015 · Doi Hiroshi, Fujiwara Masayuki, Suzuki Hitomi, et al. · Molecular and clinical oncology · 2015
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Severe oral mucositis (grade >= 3), incidence Zinc L-carnosine (polaprezinc) in any formulation (mouthwash, lozenge, mucoadhesive suspension) vs Standard oral care, no prophylaxis, azulene gargle, sodium bicarbonate mouthwash or delayed ZnC | OR 0.44 [0.18, 1.06] | 7 studies · 532 participants | Low |
Severe oral mucositis (grade >= 3), incidence Zinc L-carnosine (polaprezinc) in any formulation (mouthwash, lozenge, mucoadhesive suspension) vs Standard oral care, no prophylaxis, azulene gargle, sodium bicarbonate mouthwash or delayed ZnC | OR 0.48 [0.32, 0.72] | 7 studies · 532 participants | Low |
1 including review in total.