evidencegaps
Primary study · included by 1 review

Efficacy of locally delivered 1.2% rosuvastatin gel to non-surgical treatment of patients with chronic periodontitis: a randomized, placebo-controlled clinical trial.

Pradeep 2015 · Pradeep A R, Karvekar Shruti, Nagpal Kanika, et al. · Journal of periodontology · 2015

Included by

Adjunctive Use of Locally Delivered Statins in Periodontal Therapy and Pre-Implant Bone Regeneration: A Systematic Review and Meta-Analysis.
Non-Cochrane · intervention · 2026 · cited as Pradeep 2015 · Figures 2-4; Tables 4-5 and reference list
Outcome this study informsPooled effectEvidenceCertainty
Probing pocket depth (PPD), change from baseline (mm)
SRP plus locally delivered 1.2% rosuvastatin gel vs SRP alone (placebo gel or no gel) · 6 months
MD 1.91 [1.35, 2.48]4 studies · 211 participantsGRADE not reported
Clinical attachment level (CAL), change from baseline (mm)
SRP plus locally delivered 1.2% rosuvastatin gel vs SRP alone (placebo gel or no gel) · 6 months
MD 1.94 [1.33, 2.56]4 studies · 211 participantsGRADE not reported

1 including review in total.