Primary study · included by 2 reviews
Platelet-rich fibrin with 1% metformin for the treatment of intrabony defects in chronic periodontitis: a randomized controlled clinical trial.
Pradeep 2015 · Pradeep A R, Nagpal Kanika, Karvekar Shruti, et al. · Journal of periodontology · 2015
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Bone fill (BF) Metformin (MF) plus PRF vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined) | SMD 2.29 | NR | GRADE not reported |
Clinical attachment level (CAL) gain Metformin (MF) plus PRF vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined) | SMD 1.91 | NR | GRADE not reported |
Clinical attachment level (CAL) gain Metformin (MF) plus PRF vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined) | SMD 0.99 | NR | GRADE not reported |
Clinical attachment level (CAL) gain Metformin (MF) plus PRF vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined) | SMD 1.91 [1.37, 2.46] | 4 studies | GRADE not reported |
Bone fill (BF) Metformin (MF) plus PRF vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined) | SMD 2.29 [2.15, 2.44] | 4 studies | GRADE not reported |
Bone fill (BF) Metformin (MF) plus PRF vs PRF alone (placebo-containing PRF) · 6 and 9 months post-treatment (follow-up times combined) | SMD 2.07 | NR | GRADE not reported |
The review does not say which of its outcomes this study informs.
2 including reviews in total.