evidencegaps
Primary study · included by 1 review

Case series of 589 tooth extractions in patients under bisphosphonates therapy. Proposal of a clinical protocol supported by Nd:YAG low-level laser therapy.

Vescovi 2013 · Vescovi Paolo, Meleti Marco, Merigo Elisabetta, et al. · Medicina oral, patologia oral y cirugia bucal · 2013

Included by

Antibiotic Prophylaxis and Postoperative Therapy in Tooth Extractions for Patients at Risk of Medication-Related Osteonecrosis of the Jaw (MRONJ): A Scoping Review.
Non-Cochrane · intervention · 2025 · cited as Vescovi et al. 2013 · Table 1; Reference 26
Outcome this study informsPooled effectEvidenceCertainty
MRONJ incidence (MRONJ/bone exposure cases)
High-dose bone-modifying agent therapy vs Low-dose bone-modifying agent therapy
OR 3.26 [1.74, 6.10]16 studies · 1187 participantsGRADE not reported
MRONJ incidence (MRONJ/bone exposure cases)
High-dose bone-modifying agent therapy vs Low-dose bone-modifying agent therapy
OR 33.5 [6.3, 177.8]32 studiesGRADE not reported
MRONJ incidence (MRONJ/bone exposure cases)
High-dose bone-modifying agent therapy vs Low-dose bone-modifying agent therapy
OR 2.82 [1.46, 5.43]16 studies · 1187 participantsGRADE not reported

1 including review in total.