Primary study · included by 1 review

Resveratrol decreases periodontal breakdown and modulates local levels of cytokines during periodontitis in rats.

Casati 2013 · Casati Marcio Z, Algayer Carolina, Cardoso da Cruz Geisa, et al. · Journal of periodontology · 2013

Included by

Resveratrol as an Adjunct Therapy in Periodontal Disease: A Systematic Review and Meta-Analysis.
Non-Cochrane · intervention · 2026 · cited as Casati 2013 · Figures 2 to 4; Tables 1 to 3; References 25 to 34, 40 to 44
Outcome this study informsPooled effectEvidenceCertainty
IL-1β protein expression in gingiva
Resveratrol vs Periodontitis model without resveratrol (placebo or untreated)
SMD -0.87 [-1.49, -0.25]2 studies · 44 participantsGRADE not reported
Alveolar bone crest level (CEJ to bone crest distance, mm)
Resveratrol vs Periodontitis model without resveratrol (placebo or untreated)
MD -0.10 [-0.12, -0.08]3 studiesGRADE not reported
Alveolar bone crest level (CEJ to bone crest distance, mm)
Resveratrol vs Periodontitis model without resveratrol (placebo or untreated)
MD -0.10 [-0.12, -0.08]3 studiesGRADE not reported
Alveolar bone crest level (CEJ to bone crest distance, mm)
Resveratrol vs Periodontitis model without resveratrol (placebo or untreated)
MD -0.10 [-0.14, -0.06]3 studiesGRADE not reported
Alveolar bone crest level (CEJ to bone crest distance, mm)
Resveratrol vs Periodontitis model without resveratrol (placebo or untreated)
MD -0.10 [-0.11, -0.08]4 studies · 62 participantsGRADE not reported
Alveolar bone crest level (CEJ to bone crest distance, mm)
Resveratrol vs Periodontitis model without resveratrol (placebo or untreated)
MD -0.10 [-0.12, -0.08]4 studiesGRADE not reported
Alveolar bone crest level (CEJ to bone crest distance, mm)
Resveratrol vs Periodontitis model without resveratrol (placebo or untreated)
MD -0.10 [-0.12, -0.08]3 studiesGRADE not reported

1 including review in total.