Primary study · included by 4 reviews

Randomized clinical trial on effectiveness of silver diamine fluoride and glass ionomer in arresting dentine caries in preschool children.

Zhi et al. 2012 · Zhi Qing Hui, Lo Edward Chin Man, Lin Huan Cai · Journal of dentistry · 2012

PubMed 22892463 doi:10.1016/j.jdent.2012.08.002Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Trial PICO

Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.

Results

Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.

Included by

Caries remineralisation and arresting effect in children by professionally applied fluoride treatment - a systematic review.

Non-Cochrane · intervention · 2016 · cited as Zhi et al. 2012 · Results (Group 2); Table 2; Fig. 3; References [14]

Outcome this study informs	Pooled effect	Evidence	Certainty
Arrest of dentine caries (proportion of surfaces arrested) Professionally applied 38% silver diamine fluoride (SDF) vs Active dentine caries at baseline (single-arm before vs after proportion)	Proportion 0.659 [0.412, 0.907]	5 studies	Ungraded
Reversal / remineralisation of early enamel caries 6% sodium fluoride with 6% calcium fluoride varnish vs No treatment	One study (Xhemnica 2008) reported a significant reversal of early enamel caries using 6% NaF with 6% calcium fluoride compared with no treatment; this study was excluded from the meta-analysis.	1 study	Ungraded

Scientific evidence for the management of dentin caries lesions in pediatric dentistry: A systematic review and network meta-analysis.

Non-Cochrane · intervention · 2018 · cited as Zhi 2012 · Table 1; Table 2; Reference 26 (occlusal and smooth surface SDF 1x/2x vs LVGIC; occlusal and smooth NMA Fig 6)

Outcome this study informs	Pooled effect	Evidence	Certainty
Caries lesion arrestment Silver diamine fluoride twice annually vs Other network treatments · Various follow-up times	RANK 1	3 studies	Moderate

Silver Diamine Fluoride (SDF) Efficacy in Arresting Cavitated Caries Lesions in Primary Molars: A Systematic Review and Metanalysis.

Non-Cochrane · intervention · 2022 · cited as Zhi 2012 · Table 1; Reference 43

The review does not say which of its outcomes this study informs.

Comparative success of minimally invasive treatments for cavitated caries in primary teeth: a network meta-analysis.

Non-Cochrane · intervention · 2025 · cited as Zhi 2012 · Table 1

The review does not say which of its outcomes this study informs.

4 including reviews in total.