Primary study · included by 1 review

A novel biomimetic orthodontic bonding agent helps prevent white spot lesions adjacent to brackets.

Manfred 2013 · Manfred Lauren, Covell David A, Crowe Jennifer J, et al. · The Angle orthodontist · 2013

PubMed 22765388doi:10.2319/110811-689.1Comparative Study; Journal Article

Trial PICO

Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.

Results

Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.

Included by

Remineralization and anti-demineralization effect of orthodontic adhesives on enamel surrounding orthodontic brackets: a systematic review of in vitro studies.
Non-Cochrane · intervention · 2024 · cited as Manfred 2013 · Table 1 (study characteristics); Reference [26]
Outcome this study informsPooled effectEvidenceCertainty
Enamel remineralization / anti-demineralization extent
Orthodontic adhesives containing bioactive glass (BAG) particles/nanoparticles (including Ag-, Zn-, fluoride-, or Ga-doped BAG) vs Conventional/control orthodontic adhesive (e.g., Transbond XT) or negative control · pH cycling 14 days to 6 months (majority 14 days)
Out of 13 studies that evaluated bioactive glass particles/nanoparticles, 9 reported definitive statistically significant remineralization potential compared to control orthodontic adhesives [17, 21-24, 26-28, 31]; one…13 studiesUngraded
Enamel remineralization or anti-demineralization
Remineralizing orthodontic adhesives vs Control orthodontic adhesives · 5 days to 6 months
no estimate extracted24 studiesUngraded

1 including review in total.