evidencegaps
Primary study · included by 1 review

MicroRNA-34a affects the occurrence of laryngeal squamous cell carcinoma by targeting the antiapoptotic gene survivin.

Shen 2012 · Shen Zhisen, Zhan Guowen, Ye Dong, et al. · Medical oncology (Northwood, London, England) · 2012

Included by

Prognostic Impact of miR-34a in Head and Neck Squamous Cell Carcinoma: A Systematic Review with Meta-Analysis and Trial Sequential Analysis.
Non-Cochrane · prognostic · 2026 · cited as Shen 2012 · Table 1; Table 2; References
Outcome this study informsPooled effectEvidenceCertainty
Disease-free survival
Low tumor-tissue miR-34a expression (study-defined cut-off) vs High tumor-tissue miR-34a expression
HR 0.19 [0.00, 129.34]2 studies · 93 participantsVery low
Disease-free survival
Low tumor-tissue miR-34a expression (study-defined cut-off) vs High tumor-tissue miR-34a expression
HR 2.92 [1.24, 6.88]2 studies · 93 participantsVery low

1 including review in total.