Primary study · included by 1 review

Mutans streptococci dose response to xylitol chewing gum.

Milgrom et al. 2006 · Milgrom P, Ly K A, Roberts M C, et al. · Journal of dental research · 2006

PubMed 16434738 doi:10.1177/154405910608500212Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural

Trial PICO

Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.

Results

Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.

Included by

Clinical Effects of Sugar Substitutes on Cariogenic Bacteria: A Systematic Review and Meta-Analysis.

Non-Cochrane · intervention · 2024 · cited as Milgrom et al. 2006 · Table 1 (included studies, dental plaque); Figure 5 (xylitol vs sorbitol, plaque); ref 39

Outcome this study informs	Pooled effect	Evidence	Certainty
Change in Mutans streptococci (MS) count in dental plaque Xylitol (low-intensity sweetener/sugar alcohol) in food products (chewing gum, milk, candy, or tablets) vs Sorbitol (low-intensity sweetener) · Post-consumption endpoint (varied durations across trials)	SMD -0.45 [-0.69, -0.21]	4 studies · 323 participants	Ungraded

1 including review in total.